John W Holloway Selected Research

Guanine

1/2022	Newborn DNA methylation and asthma acquisition across adolescence and early adulthood.
1/2021	Sex-specific associations of asthma acquisition with changes in DNA methylation during adolescence.
1/2021	Association of Maternal DNA Methylation and Offspring Birthweight.
8/2018	SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts.
12/2016	Tetanus vaccination is associated with differential DNA-methylation: Reduces the risk of asthma in adolescence.
1/2016	DNA methylation and genetic polymorphisms of the Leptin gene interact to influence lung function outcomes and asthma at 18 years of age.
1/2013	The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years.

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John W Holloway Research Topics

Disease

54	Asthma (Bronchial Asthma) 02/2022 - 07/2002
11	Hypersensitivity (Allergy) 01/2022 - 05/2002
10	Eczema 10/2022 - 05/2002
7	Inflammation (Inflammations) 10/2020 - 07/2002
5	Wounds and Injuries (Trauma) 01/2018 - 11/2013
4	Chronic Obstructive Pulmonary Disease (COPD) 08/2018 - 08/2011
3	Rhinitis 11/2021 - 01/2014
3	Birth Weight (Birth Weights) 01/2021 - 01/2018
3	Respiratory Sounds (Crackle) 10/2014 - 12/2010
3	Genetic Predisposition to Disease (Genetic Predisposition) 10/2013 - 01/2011
3	Airway Remodeling 01/2006 - 07/2002
2	Food Hypersensitivity (Food Allergy) 11/2021 - 10/2014
2	Eosinophilia 01/2021 - 01/2012
2	Seasonal Allergic Rhinitis (Hay Fever) 01/2014 - 08/2013
2	Atopic Dermatitis (Atopic Eczema) 10/2013 - 02/2010
2	Lung Injury 05/2012 - 01/2005
1	Human Influenza (Influenza) 01/2022
1	COVID-19 01/2022
1	Virus Diseases (Viral Diseases) 07/2021
1	Overweight 01/2021
1	Fatty Liver 01/2021
1	Obesity 01/2021
1	Body Weight (Weight, Body) 01/2021
1	Pregnancy Complications 01/2020
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 06/2019
1	Skin Neoplasms (Skin Cancer) 01/2018
1	Osteoporosis 01/2017
1	Type 2 Diabetes Mellitus (MODY) 01/2017
1	Tetanus 12/2016
1	Ciliary Motility Disorders (Primary Ciliary Dyskinesia) 04/2016
1	Bronchial Hyperreactivity 04/2014
1	Lung Neoplasms (Lung Cancer) 10/2013

Drug/Important Bio-Agent (IBA)

9	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 10/2011
8	Filaggrin ProteinsIBA 10/2022 - 02/2007
7	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2013
7	CytosineIBA 01/2022 - 01/2013
7	CytokinesIBA 01/2022 - 07/2002
7	GuanineIBA 01/2022 - 01/2013
7	Phosphates (Orthophosphate)IBA 01/2022 - 01/2013
7	AllergensIBA 11/2021 - 07/2002
6	Biological ProductsIBA 01/2022 - 07/2013
6	Immunoglobulin E (IgE)IBA 01/2017 - 01/2009
5	MicroRNAs (MicroRNA)IBA 01/2021 - 11/2013
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2004
5	Interleukin-13IBA 01/2014 - 07/2002
4	Toll-Like Receptor 4IBA 10/2009 - 09/2003
3	NucleotidesIBA 01/2022 - 08/2013
3	Protein Isoforms (Isoforms)IBA 01/2020 - 07/2004
3	SmokeIBA 12/2018 - 02/2007
3	AntioxidantsIBA 01/2018 - 04/2010
3	Interleukin-4 (Interleukin 4)IBA 01/2014 - 07/2002
3	EndotoxinsIBA 06/2010 - 01/2005
3	Metalloproteases (Metalloproteinases)IBA 06/2008 - 08/2003
2	Dihydrotachysterol (AT 10)IBA 02/2022 - 01/2018
2	VaccinesIBA 01/2022 - 12/2016
2	RNA (Ribonucleic Acid)IBA 07/2021 - 01/2021
2	Interleukin-33IBA 01/2021 - 01/2014
2	Messenger RNA (mRNA)IBA 01/2020 - 01/2019
2	SeleniumIBA 01/2018 - 04/2015
2	ZincIBA 01/2018 - 08/2003
2	Vitamin D FDA LinkGeneric 01/2017 - 08/2011
2	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2017 - 12/2010
2	Methacholine Chloride (Methacholine)FDA Link 04/2014 - 09/2013
2	ErbB Receptors (EGF Receptor)IBA 08/2013 - 07/2002
2	EnzymesIBA 09/2012 - 04/2010
2	LeukotrienesIBA 09/2012 - 01/2012
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2012 - 03/2007
2	Lymphotoxin-alpha (Lymphotoxin)IBA 10/2009 - 01/2005
2	DisintegrinsIBA 06/2008 - 07/2006
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 02/2007 - 11/2005
2	Peptide Hydrolases (Proteases)FDA Link 01/2006 - 08/2004
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2005 - 07/2002
1	Cadherins (E-Cadherin)IBA 01/2022
1	Immunoglobulins (Immunoglobulin)IBA 01/2022
1	Nucleosomes (Nucleosome)IBA 01/2022
1	Small Cytoplasmic RNAIBA 07/2021
1	Protons (Proton)IBA 01/2021
1	AcidsIBA 01/2021
1	Bronchodilator Agents (Bronchodilators)IBA 01/2020
1	Adenine FDA LinkGeneric 06/2019
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2019
1	MucinsIBA 01/2019
1	Coal Tar (Estar)IBA 12/2018
1	VitaminsIBA 01/2018
1	Coloring Agents (Dyes)IBA 01/2018
1	Carotenoids (Carotene)IBA 01/2018
1	Ion Channels (Ion Channel)IBA 01/2017
1	Cholecalciferol (Vitamin D3)FDA Link 01/2017
1	Axonemal DyneinsIBA 04/2016
1	LeptinIBA 01/2016
1	GoldIBA 01/2016
1	Phospholipid Hydroperoxide Glutathione PeroxidaseIBA 04/2015
1	Indicators and Reagents (Reagents)IBA 01/2015
1	phthalic acid (phthalate)IBA 01/2015
1	montelukast (Singulair)FDA Link 10/2014
1	insulin receptor-related receptor (IRR)IBA 10/2014
1	Transcription Factors (Transcription Factor)IBA 01/2014
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2014
1	Oral ContraceptivesIBA 01/2014

Therapy/Procedure

1	Cesarean Section (Caesarean Section) 01/2020